Journal Article

Faster calcium recovery and membrane resealing in repeated sonoporation for delivery improvement

J Shi, T Han, ACH Yu, P Qin

Journal of Controlled Release, 352, 385-398, 2022.

Time-resolved wall shear rate mapping using high-frame-rate ultrasound imaging

AJY Chee, CK Ho, BYS Yiu, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69(12), 3367-3381, 2022.

Artificial-intelligence-enhanced ultrasound flow imaging at the edge

H Nahas, S Huver, BYS Yiu, CM Kallweit, AJY Chee, ACH Yu

IEEE Micro, 42(6), 96-106, 2022.

Unfocused field analysis of a density-tapered spiral array for high-volume-rate 3D ultrasound imaging

R Maffett, E Boni, AJY Chee, BYS Yiu, AS Savoia, A Ramalli, P Tortoli, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69(10), 2810-2822, 2022.

Minimizing image quality loss after channel count reduction for plane wave ultrasound via deep learning inference

D Xiao, WMK Pitman, BYS Yiu, AJY Chee, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69(10), 2849-2861, 2022.

Sonoporation of immune cells: heterogeneous impact on lymphocytes, monocytes and granulocytes

X Duan, SY Lo, JCY Lee, JMF Wan, ACH Yu

Ultrasound in Medicine and Biology, 48(7), 1268-1281, 2022.

Spatiotemporal dynamics and mechanisms of actin cytoskeletal re-modeling in cells perforated by ultrasound-driven microbubbles

C Jia, J Shi, T Han, ACH Yu, P Qin

Ultrasound in Medicine and Biology, 48(5), 760-777, 2022.

Embedded 3D printing of ultrasound‐compatible arterial phantoms with biomimetic elasticity

Y Wu, AJY Chee, H Golzar, ACH Yu, XS Tang

Advanced Functional Materials, 32(25), 2110153, 2022.

Quantitative blood flow measurements in the common carotid artery: a comparative study of high-frame-rate ultrasound vector flow imaging, pulsed wave Doppler, and phase contrast magnetic resonance imaging

Y Du, H Ding, L He, BYS Yiu, L Deng, ACH Yu, L Zhu

Diagnostics, 12(3), 690, 2022.

Ultrasound-mediated drug delivery: sonoporation mechanisms, biophysics, and critical factors

J Tu, ACH Yu

BME Frontiers, 2022, 9807347, 2022.

An enhanced, rational model to study acoustic vaporization dynamics of a bubble encapsulated within a nonlinearly elastic shell

M Ghasemi, ACH Yu, S Sivaloganathan

Ultrasonics Sonochemistry, 83, 105948, 2022.

Improving temporal stability of stable cavitation activity of circulating microbubbles using a closed-loop controller based on pulse-length regulation

C Tan, B Yan, T Han, ACH Yu, P Qin

Ultrasonics Sonochemistry, 83, 105948, 2022.

In situ and intraoperative detection of the ureter injury using a highly sensitive piezoresistive sensor with a tunable porous structure

S Wang, G Chen, B Yao, AJY Chee, Z Wang, P Du, S Qu, ACH Yu

ACS Applied Materials and Interfaces, 13, 21669-21679, 2021.

Sonoporation generates downstream cellular impact after membrane resealing

X Duan, Q Zhou, JMF Wan, ACH Yu

Scientific Reports, 11, 5161, 2021.

Plasmalemmal blebbing dynamics specifically involved in the reversibly perforated cell by ultrasound-driven microbubbles

C Jia, J Shi, Y Yao, T Han, ACH Yu, P Qin

Ultrasound in Medicine and Biology, 47(3), 733-750, 2021.

Helical toroid phantom for 3-D flow imaging investigations

AJY Chee, T Ishii, BYS Yiu, ACH Yu

Physics in Medicine and Biology, 66(4), 045029, 2021.

Evaluation of the properties of daughter bubbles generated by inertial cavitation of preformed bubbles

Y Li, C Tan, B Yan, T Han, ACH Yu, P Qin

Ultrasonics Sonochemistry, 72, 105400, 2021.

A deep learning approach to resolve aliasing artifacts in ultrasound color flow imaging

H Nahas, JS Au, T Ishii, BYS Yiu, AJY Chee, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 67(12), 2615-2628, 2020.

Contrast-enhanced urodynamic vector projectile imaging (CE-UroVPI) for urethral voiding visualization: principles and phantom studies

T Ishii, H Nahas, BYS Yiu, AJY Chee, ACH Yu

Urology, 140, 171-177, 2020.

Ultrasound vector projectile imaging for detection of altered carotid bifurcation hemodynamics during reductions in cardiac output

JS Au, BYS Yiu, H So, AJY Chee, DK Greaves, RL Hughson, ACH Yu

Medical Physics, 47(2), 431-440, 2020.

Case studies in physiology: visualization of blood recirculation in a femoral artery 'trifurcation' using ultrasound vector flow imaging

JS Au, BYS Yiu, ACH Yu

Journal of Applied Physiology, 127(6), 1809-1813, 2019.

Cellular bioeffect investigations on low-intensity pulsed ultrasound and sonoporation: platform design and flow cytometry protocol

X Duan, ACH Yu, JMF Wan

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 66(9), 1422-1434, 2019.

Deformable phantoms of the prostatic urinary tract for urodynamic investigations

T Ishii, CK Ho, H Nahas, BYS Yiu, AJY Chee, ACH Yu

Medical Physics, 46(7), 3034-3043, 2019.

Live ultrasound color encoded speckle imaging platform for real-time complex flow visualization in vivo

BYS Yiu, M Walczak, M Lewandowski, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 66(4), 656-669, 2019.

High frame rate Doppler ultrasound bandwidth imaging for flow instability mapping

BYS Yiu, AJY Chee, G Tang, W Luo, ACH Yu

Medical Physics, 46(4), 1620-1633, 2019.

Effects of ultrasound pulse parameters on cavitation properties of the flowing microbubbles under physiologically relevant conditions

M Cheng, F Li, T Han, ACH Yu, P Qin

Ultrasonics Sonochemistry, 52, 512-521, 2019.

Effects of aspect ratio, wall thickness and hypertension in the patient specific computational modeling of cerebral aneurysms using fluid-structure interaction analysis

HT Sun, KY Sze, AYS Tang, ACO Tsang, ACH Yu, KW Chow

Engineering Applications of Computational Fluid Mechanics, 13(1), 229-244, 2019.

Ultrasound imaging and measurement of choroidal blood flow

R Urs, JA Ketterling, ACH Yu, BYS Yiu, HO Lloyd, RH Silverman

Translational Vision Science and Technology, 7(5), 5, 2018.

Ultrasound open platforms for next-generation imaging technique development

E Boni, ACH Yu, S Freear, JA Jensen, P Tortoli

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 65(7), 1078-1092, 2018.

Generation of reactive oxygen species in heterogeneously sonoporated cells by microbubbles with single-pulse ultrasound

C Jia, L Xu, P Cai, ACH Yu, P Qin

Ultrasound in Medicine and Biology, 44(5), 1074-1085, 2018.

Arterial phantoms with regional variations in wall stiffness and thickness

AJY Chee, BYS Yiu, CK Ho, ACH Yu

Ultrasound in Medicine and Biology, 44(4), 872-883, 2018.

Receiver operating characteristic analysis of eigen-based clutter filters for ultrasound color flow imaging

AJY Chee, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 65(3), 390-399, 2018.

Mechanistic understanding the bioeffects of ultrasound-driven microbubbles to enhance macromolecule delivery

P Qin, T Han, ACH Yu, L Xu

Journal of Controlled Release, 272, 169-181, 2018.

Riding the plane wave: Considerations for in vivo study designs employing high frame rate ultrasound

JS Au, RL Hughson, ACH Yu

Applied Sciences, 8, 286, 2018.

The effect of downstream resistance on the flow diverter treatment of a cerebral aneurysm at a bifurcation: a joint computational-experimental study

ACO Tsang, BYS Yiu, AYS Tang, WC Chung, GKK Leung, AKK Poon, ACH Yu, SSM Lai, KW Chow

Journal of Hydrodynamics, 30(5), 803-814, 2018.

A brief review of ultrasound imaging and video

ACH Yu

Handbook of Speckle Filtering and Tracking in Cardiovascular Ultrasound Imaging and Video (C Loizou, C Pattichis, and J d’Hooge, Eds.), , 3-24, 2018.

Spiral flow phantom for ultrasound flow imaging experimentation

BYS Yiu, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64(12), 1840-1848, 2017.

High-speed, high-frequency ultrasound, in utero vector-flow imaging of mouse embryos

JA Ketterling, O Aristizábal, BYS Yiu, DH Turnbull, CKL Phoon, ACH Yu, RH Silverman

Scientific Reports, 7, 16658, 2017.

Vector flow visualization of urinary flow dynamics in a bladder outlet obstruction model

T Ishii, BYS Yiu, ACH Yu

Ultrasound in Medicine and Biology, 43(11), 2601-2610, 2017.

Enhanced porosity and permeability of three-dimensional alginate scaffolds via acoustic microstreaming induced by low-intensity pulsed ultrasound

G Guo, Y Ma, Y Guo, C Zhang, J Tu, X Guo, ACH Yu, J Wu, D Zhang

Ultrasonics Sonochemistry, 37, 279-285, 2017.

Effect of acoustic parameters on the cavitation behavior of SonoVue microbubbles induced by pulsed ultrasound

Y Lin, L Lin, M Cheng, L Jin, L Du, T Han, L Xu, ACH Yu, P Qin

Ultrasonics Sonochemistry, 35, 176-184, 2017.

Wall-less flow phantoms with tortuous vascular geometries: design principles and a patient-specific model fabrication example

CK Ho, AJY Chee, BYS Yiu, ACO Tsang, KW Chow, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64(1), 25-38, 2017.

A GPU-parallelized eigen-based clutter filter framework for ultrasound color flow imaging

AJY Chee, BYS Yiu, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64(1), 150-163, 2017.

Methods and protocols: engine for the next wave of biomedical ultrasound innovations

ACH Yu, JA Hossack

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64(1), 6-10, 2017.

Effect of non-acoustic parameters on heterogeneous sonoporation mediated by single-pulse ultrasound and microbubbles

P Qin, L Xu, T Han, L Du, ACH Yu

Ultrasonics Sonochemistry, 31, 107-115, 2016.

Least-squares multi-angle Doppler estimators for plane wave vector flow imaging

BYS Yiu, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 63(11), 1733-1744, 2016.

Walled carotid bifurcation phantoms for imaging investigations of vessel wall motion and blood flow dynamics

AJY Chee, CK Ho, BYS Yiu, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 63(11), 1852-1864, 2016.

Investigation of crossbeam multi-receiver configurations for accurate 3D-vector Doppler velocity estimation

B Hussain, BYS Yiu, ACH Yu, JC Lacefield, TL Poepping

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 63(11), 1786-1798, 2016.

Ultrasound vector flow imaging: Part I. sequential systems

JA Jensen, SI Nikolov, ACH Yu, D Garcia

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 63(11), 1704-1721, 2016.

Ultrasound vector flow imaging: Part II. parallel systems

JA Jensen, SI Nikolov, ACH Yu, D Garcia

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 63(11), 1722-1732, 2016.

High sensitivity, wearable, piezoresistive pressure sensors based on irregular micro-hump structures and its applications in body motion sensing

Z Wang, S Wang, J Zeng, X Ren, AJY Chee, BYS Yiu, WC Chung, ACH Yu, RC Roberts, ACO Tsang, KW Chow, PKL Chan

Small, 27(28), 3827-3836, 2016.

A joint computational-experimental study of intracranial aneurysms: importance of the aspect ratio

SSM Lai, AYS Tang, ACO Tsang, GKK Leung, ACH Yu, KW Chow

Journal of Hydrodynamics, 28(3), 462-472, 2016.

Flow velocity mapping using high frame rate plane wave ultrasound and microbubble contrast agents

CH Leow, E Bazigou, RJ Eckersley, ACH Yu, PD Weinberg, MX Tang

Ultrasound in Medicine and Biology, 41(11), 2913-2925, 2015.

Plane wave compounding based on a joint transmitting-receiving adaptive beamformer

Y Zhao, Y Wang, X Zeng, J Yu, BYS Yiu, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 62(8), 1440-1452, 2015.

2D arterial wall motion imaging using ultrafast ultrasound and transverse oscillations

S Salles, AJY Chee, D Garcia, ACH Yu, D Vray, H Liebgott

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 62(6), 1047-1058, 2015.

Computational fluid dynamics study of bifurcation aneurysms treated with pipeline embolization device: side branch diameter study

AYS Tang, WC Chung, ETY Liu, JQ Qu, ACO Tsang, GKK Leung, KM Leung, ACH Yu, KW Chow

Journal of Medical and Biological Engineering, 35(3), 293-304, 2015.

Software-based high-level synthesis design of FPGA beamformers for synthetic aperture imaging

J Amaro, BYS Yiu, G Falcao, M Gomes, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 62(5), 862-870, 2015.

GPU-based minimum variance beamformer for synthetic aperture imaging of the eye

BYS Yiu, ACH Yu

Ultrasound in Medicine and Biology, 41(3), 871-883, 2015.

Membrane blebbing as a recovery manoeuvre in site-specific sonoporation mediated by targeted microbubbles

RS Leow, JMF Wan, ACH Yu

Journal of The Royal Society Interface, 12(105), 20150029, 2015.

Blood flow in intracranial aneurysms treated with pipeline embolization devices: computational simulation and verification with Doppler ultrasonography on phantom models

ACO Tsang, SSM Lai, WC Chung, AYS Tang, GKK Leung, AKK Poon, ACH Yu, KW Chow

Ultrasonography, 34(2), 98-108, 2015.

Vector projectile imaging: time-resolved dynamic visualization of complex flow patterns

BYS Yiu, SSM Lai, ACH Yu

Ultrasound in Medicine and Biology, 40(9), 2295-2309, 2014.

Cytomechanical perturbations during low intensity ultrasound pulsing

Y Hu, JMF Wan, ACH Yu

Ultrasound in Medicine and Biology, 40(7), 1587-1598, 2014.

Sonoporation-induced depolarization of plasma membrane potential: analysis of heterogeneous impact

P Qin, L Xu, Y Hu, W Zhong, P Cai, L Du, L Jin, ACH Yu

Ultrasound in Medicine and Biology, 40(5), 979-989, 2014.

Microbubble-mediated sonoporation amplified lipid peroxidation of Jurkat cells

KS Leung, X Chen, W Zhong, ACH Yu, CYJ Lee

Chemistry and Physics of Lipids, 180, 53-60, 2014.

Single-site sonoporation disrupts actin cytoskeleton organization

X Chen, RS Leow, Y Hu, JMF Wan, ACH Yu

Journal of The Royal Society Interface, 11(95), 20140071, 2014.

Membrane perforation and recovery dynamics in microbubble-mediated sonoporation

Y Hu, JMF Wan, ACH Yu

Ultrasound in Medicine and Biology, 39(12), 2393-2405, 2013.

Induction of endoplasmic reticulum stress by sonoporation: linkage to mitochondria-mediated apoptosis initiation

W Zhong, X Chen, P Jiang, JMF Wan, P Qin, ACH Yu

Ultrasound in Medicine and Biology, 39(12), 2382-2392, 2013.

The effects of stent porosity on the endovascular treatment of intracranial aneurysms located near a bifurcation

AYS Tang, HHN Chan, ACO Tsang, GKK Leung, KM Leung, ACH Yu, KW Chow

Journal of Biomedical Science and Engineering, 6(8), 812-822, 2013.

Design of anthropomorphic flow phantoms based on rapid prototyping of compliant vessel geometries

SSM Lai, BYS Yiu, AKK Poon, ACH Yu

Ultrasound in Medicine and Biology, 39(9), 1654-1664, 2013.

Sonoporation as a cellular stress: induction of morphological repression and developmental delays

X Chen, JMF Wan, ACH Yu

Ultrasound in Medicine and Biology, 39(6), 1075-1086, 2013.

High frame rate ultrasound color-encoded speckle imaging of complex flow dynamics

BYS Yiu, ACH Yu

Ultrasound in Medicine and Biology, 39(6), 1015-1025, 2013.

Ultrasound can modulate neuronal development: impact on neurite growth and cell body morphology

Y Hu, W Zhong, JMF Wan, ACH Yu

Ultrasound in Medicine and Biology, 39(5), 915-925, 2013.

Subcellular impact of sonoporation on plant cells: issues to be addressed in ultrasound-mediated gene transfer

P Qin, L Xu, P Cai, Y Hu, ACH Yu

Ultrasonics Sonochemistry, 20(1), 247-253, 2013.

Ultrasound-microbubble mediated cavitation of plant cells: effects on morphology and viability

P Qin, L Xu, W Zhong, ACH Yu

Ultrasound in Medicine and Biology, 38(6), 1085-1096, 2012.

Multi-channel pre-beamformed data acquisition system for research on advanced ultrasound imaging methods

CCP Cheung, ACH Yu, N Salimi, BYS Yiu, IKH Tsang, B Kerby, RZ Azar, K Dickie

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 59(2), 243-253, 2012.

Design space exploration of adaptive beamforming acceleration for bedside and portable medical ultrasound imaging

J Chen, BYS Yiu, B Hamilton, ACH Yu, HKH So

ACM SIGARCH Computer Architecture News, 39(4), 20-25, 2011.

Sonoporation induces apoptosis and cell cycle arrest in human promyelocytic leukemia cells

W Zhong, WH Sit, JMF Wan, ACH Yu

Ultrasound in Medicine and Biology, 37(12), 2149-2159, 2011.

Medical ultrasound imaging: to GPU or not to GPU?

HKH So, J Chen, BYS Yiu, ACH Yu

IEEE Micro, 31(5), 54-65, 2011.

GPU-based beamformer: fast realization of plane wave compounding and synthetic aperture imaging

BYS Yiu, IKH Tsang, ACH Yu

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 58(8), 1698-1705, 2011.

Eigen-based clutter filter design for ultrasound color flow imaging: a review

ACH Yu, L Lovstakken

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 57(5), 1096-1111, 2010.

Single-ensemble-based eigen-processing methods for color flow imaging -- Part II. The Matrix Pencil estimator

ACH Yu, RSC Cobbold

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 55(3), 573-586, 2008.

Single-ensemble-based eigen-processing methods for color flow imaging -- Part I. The Hankel-SVD filter

ACH Yu, RSC Cobbold

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 55(3), 559-572, 2008.

An automated carotid pulse assessment approach using Doppler ultrasound

ACH Yu, E Cohen-Solal, S Ayati

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 55(3), 1072-1081, 2008.

Frequency-based signal processing for ultrasound color flow imaging

ACH Yu, KW Johnston, RSC Cobbold

Canadian Acoustics, 35(2), 11-23, 2007.

Coded excitation methods for ultrasound harmonic imaging

R Arshadi, ACH Yu, RSC Cobbold

Canadian Acoustics, 35(2), 35-46, 2007.

Transit-time broadening in pulsed Doppler ultrasound: a generalized amplitude modulation model

ACH Yu, AH Steinman, RSC Cobbold

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 53(3), 530-541, 2006.

Effects of beam steering in pulsed-wave ultrasound velocity estimation

AH Steinman, ACH Yu, KW Johnston, RSC Cobbold

Ultrasound in Medicine and Biology, 31(8), 1073-1082, 2005.
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